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- Coated with medication that is slowly released to prevent the artery from becoming blocked again.
- The medication helps reduce the risk of restenosis (re-narrowing of the artery)
Overview:
Drug-Eluting Stents (DES) are advanced stents used in interventional cardiology to treat narrowed or blocked coronary arteries. They consist of a metal stent coated with a polymer that gradually releases medication to prevent the re-narrowing of the artery (restenosis). DES have significantly reduced the incidence of restenosis compared to Bare Metal Stents (BMS).
Attributes
- **Material:** Typically made of cobalt-chromium or platinum-chromium.
- **Coating:** Polymer coating that releases antiproliferative drugs.
- **Medication:** Drugs such as sirolimus, everolimus, zotarolimus, or paclitaxel to inhibit cell proliferation.
- **Design:** Mesh-like tubular structure that provides scaffolding to the artery.
- **Diameter and Length:** Available in various sizes to suit different artery diameters and lesion lengths.
- **Flexibility and Radial Strength:** Engineered for optimal flexibility and strength to navigate arteries and maintain patency.
Brands, Manufacturers, SKU Numbers, and Corporate Parents
1. **Abbott Vascular**
- **Brand:** Xience
- **Manufacture:** Abbott Laboratories
- **SKU Number:** Example: G308391234120 (specific SKUs vary by size and model).
- **Corporate Parent:** Abbott Laboratories
- **Drug:** Everolimus
2. **Boston Scientific**
- **Brand:** Promus
- **Manufacture:** Boston Scientific Corporation
- **SKU Number:** Example: 1012456-001 (specific SKUs vary by size and model).
- **Corporate Parent:** Boston Scientific Corporation
- **Drug:** Everolimus
3. **Medtronic**
- **Brand:** Resolute Onyx
- **Manufacture:** Medtronic
- **SKU Number:** Example: RDE1220M-220 (specific SKUs vary by size and model).
- **Corporate Parent:** Medtronic, Inc.
- **Drug:** Zotarolimus
4. **BIOTRONIK**
- **Brand:** Orsiro
- **Manufacture:** BIOTRONIK
- **SKU Number:** Example: 4195007 (specific SKUs vary by size and model).
- **Corporate Parent:** BIOTRONIK SE & Co. KG
- **Drug:** Sirolimus
5. **Terumo**
- **Brand:** Ultimaster
- **Manufacture:** Terumo Corporation
- **SKU Number:** Example: US13960 (specific SKUs vary by size and model).
- **Corporate Parent:** Terumo Corporation
- **Drug:** Sirolimus
6. **Cook Medical**
- **Brand:** Zilver PTX
- **Manufacture:** Cook Medical Inc.
- **SKU Number:** Example: ZPTX-10-100-225 (specific SKUs vary by size and model).
- **Corporate Parent:** Cook Group Incorporated
- **Drug:** Paclitaxel
Additional Notable Brands
7. **Cordis (a Cardinal Health company)**
- **Brand:** Cypher
- **Manufacture:** Cordis
- **SKU Number:** Example: SCX1828 (specific SKUs vary by size and model).
- **Corporate Parent:** Cardinal Health
- **Drug:** Sirolimus
8. **B. Braun**
- **Brand:** Coroflex ISAR
- **Manufacture:** B. Braun Melsungen AG
- **SKU Number:** Example: 823021 (specific SKUs vary by size and model).
- **Corporate Parent:** B. Braun Melsungen AG
- **Drug:** Sirolimus
Conclusion
Drug-Eluting Stents have revolutionized the treatment of coronary artery disease by combining mechanical support with targeted drug delivery. This combination significantly reduces the risk of restenosis, offering better long-term outcomes for patients. The variety of brands and specific drug coatings allows for tailored treatment options based on individual patient needs and clinical scenarios.